Research shows that GW-501516, also known as Cardarine, binds to the PPAR receptor which in turn both activates AMP-activated protein kinase and gives stimulation to glucose uptake in skeletal muscle tissue. In this case the reaction creates a rapid increase in fat loss as well as increase in the expression of the gene that is involved in disbursement of energy. Hence in taking just the first dose of GW-501516 will increase overall energy to a user. Another benefit of GW-501516 is the fact that is non catabolic giving a user ability to lose fat without sacrificing muscle loss. GW-501516 contributes to overall health through stimulating pathways involved with exercise and also has shown in studies to dramatically increase HDL(good cholesterol) levels and decrease LDL(bad cholesterol) levels. In studies GW-501516 has shown to drastically improve endurance by increasing VO2MAX which provides maximum output via exercise. Due to its increase in energy and endurance GW-501516 is a SARM shown to give a user more power for strength and drastically increase athletic potential otherwise that could be unobtainable.
[2-methyl-4-[[[4-methyl-2-[4-(trifloromethyl)phenyl]-1,3-thiazol-5-yl]methyl]sulfanyl]phenoxy] acetic acid